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The Analytical Scientist / Issues / 2026 / April / Plasmonic COF Nanofilms Expand the Reach of Mass Spectrometry Imaging
Mass Spectrometry Sample Preparation

Plasmonic COF Nanofilms Expand the Reach of Mass Spectrometry Imaging

A gold-decorated covalent organic framework grown on titanium dioxide nanotubes enables matrix-free imaging across plants, fingerprints, fruits, and brain tissue

04/07/2026 1 min read
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Top Institutions in Mass Spectrometry Imaging and Analytical Chemistry

Leading institutions employ interdisciplinary approaches combining nanotechnology, analytical chemistry, and biomedical imaging to develop and apply novel mass spectrometry imaging platforms, emphasizing matrix-free methods and plasmonic enhancements for improved sensitivity and spatial resolution.

  • #1

    Massachusetts Institute of Technology (MIT)

    Cambridge, MA

    MIT leads in developing cutting-edge mass spectrometry imaging technologies, integrating nanomaterials and plasmonics to enhance imaging capabilities, supported by strong interdisciplinary research centers.

    Key Differentiators

    • Analytical Chemistry
    • Nanotechnology
    • Biomedical Imaging
  • #2

    Stanford University

    Stanford, CA

    Stanford has a robust program in mass spectrometry imaging, focusing on novel sample preparation techniques and nanomaterial applications to improve imaging of biological tissues.

    Key Differentiators

    • Mass Spectrometry
    • Nanomaterials
    • Biomedical Engineering
  • #3

    University of California, San Francisco (UCSF)

    San Francisco, CA

    UCSF excels in applying mass spectrometry imaging to neurological tissues, combining advanced imaging techniques with clinical research on brain metabolism and pathology.

    Key Differentiators

    • Biomedical Imaging
    • Mass Spectrometry
    • Neuroscience
  • #4

    The Scripps Research Institute

    La Jolla, CA

    Scripps Research is known for innovative chemical biology approaches and development of novel mass spectrometry imaging substrates and methods.

    Key Differentiators

    • Analytical Chemistry
    • Mass Spectrometry
    • Chemical Biology

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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