5 Key Takeaways

• 1

  Researchers developed a nanostructured surface to enhance mass spectrometry imaging across diverse sample types.

• 2

  The platform utilizes gold nanoparticle-decorated COF nanofilms combined with titanium dioxide nanotubes for improved imaging.

• 3

  This method produces cleaner low-mass spectra and stronger ion signals, facilitating various sample-preparation workflows.

• 4

  The technique successfully mapped pollutants and metabolites in cowpea seedlings, revealing movement patterns of polar compounds.

• 5

  The substrate's effectiveness stems from the synergy of plasmonic enhancement, charge-transfer effects, and a structured scaffold.