Hidden Drugs Revealed By Tandem Mass Spectrometry
December 17, 2025
By matching mass spectra to curated references, the GNPS Drug Library links patient samples to over 2,000 drugs, metabolites, and environmental chemicals
2 min read
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Metabolomics & Lipidomics
Mass Spectrometry
Metabolomics & Lipidomics
Trends & Challenges
Data & AI
Opinion & Personal Narratives
Lighting the Way Forward for Metabolomics
By Alexander Makarov, Bashar Amer, Susan S. Bird, ..et al.
December 15, 2025
Advanced software tools and self-correcting instruments could soon put the dark metabolome debate to bed, argue Alexander Makarov and the Thermo Fisher Scientific team
4 min read
Accelerating Biomarker Discovery with AI-Enhanced Omics
By Henry Thomas
December 11, 2025
By fusing multi-omics data with AI, Sapient Founder Mo Jain believes researchers will close the gap between molecular measurement and clinical meaning
10 min read
Truth, Love, and Lipidomics
By Henry Thomas
December 3, 2025
A moment of national change opened the door for Michal Holčapek to build a career defined by analytical precision and clinical impact in lipidomics
8 min read
New Workflow for Precise Bile Acid Profiling and Multi-Omics Discovery
November 27, 2025
SCIEX introduces a high-resolution, EAD-enabled LC-MS/MS workflow powered by the ZenoTOF 8600 to overcome long-standing challenges in bile acid analysis
1 min read
Formic Acid Boosts LC-MS Metabolomics Sensitivity
November 20, 2025
A small tweak to sample prep – formic acid pretreatment – enhances LC–MS sensitivity and metabolome coverage without compromising reproducibility
2 min read
AEC-MS Enables Robust Analysis of Polar and Ionic Metabolites
October 8, 2025
A new protocol provides a practical solution for large-scale metabolomics, linking molecular pathways to health and disease
2 min read
Cracking the Lipidomics Code With LC=CL
By Henry Thomas
September 26, 2025
A new computational tool allows routine, high-throughput identification of omega positions in lipids from conventional LC–MS/MS data
6 min read
The Past, Present, and Future of the “Dark Metabolome”
By James Strachan
September 23, 2025
Oliver Jones traces the evolution of a contested concept – and what it means for the future of metabolomics
5 min read
How Mutations Affecting Purine Metabolism Shaped the Human Brain
September 11, 2025
Mouse models with human-specific ADSL variants have sex-specific effects on brain function
4 min read
