Objective:

To explore the distinctions between untargeted and non-targeted screening in metabolomics and other fields.

Approach:

Key Findings:

• Experts noted a cultural difference in the use of 'untargeted' and 'non-targeted' screening.
• Fully untargeted screening is characterized by a lack of knowledge about what is being searched for or found, while non-targeted screening involves pre-selected components.
• Confusion in terminology arises from different methodologies in metabolomics and environmental analysis.
• Panelists highlighted the absence of a clear distinction between suspect screening, non-targeted screening, and untargeted screening.

Interpretation:

The discussion emphasizes the importance of clear terminology to facilitate effective communication among professionals across different fields.

Limitations:

• Definitions of untargeted and non-targeted screening vary significantly among experts.
• The discussion may not reach a consensus due to the diverse perspectives of the panelists.

Conclusion:

Recognizing the varying interpretations of these terms is crucial for improving communication and collaboration among researchers.

Sources:

• New Frontiers in Non-Target Screening: Roundtable Symposium
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