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The Analytical Scientist / Issues / 2026 / April / From Spectra to Structure: An Interview with Novogaia’s Tess Bevers
Mass Spectrometry Data and AI Metabolomics & Lipidomics

From Spectra to Structure: An Interview with Novogaia’s Tess Bevers

Novogaia’s transformer-based model converts untargeted mass spectra into structural predictions for early-stage drug discovery

By Henry Thomas 04/15/2026 7 min read
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Top Institutions in Computational Metabolomics and Natural Product Drug Discovery

Leading institutions integrate cutting-edge mass spectrometry technology with computational approaches including machine learning and AI to analyze complex metabolomic data. They develop and apply predictive models that transform spectral data into structural hypotheses, accelerating natural product identification and drug development workflows.

  • #1

    Broad Institute of MIT and Harvard

    Cambridge, MA

    The Broad Institute is a pioneer in integrating large-scale omics data with AI-driven computational models, including metabolomics and natural product discovery, supported by collaborations across MIT and Harvard.

    Key Differentiators

    • Computational Biology
    • Metabolomics
    • Machine Learning
    • Mass Spectrometry
  • #2

    Scripps Research Institute

    La Jolla, CA

    Scripps Research has a long-standing reputation in natural product chemistry and mass spectrometry, with strong expertise in computational approaches to structure elucidation and drug discovery.

    Key Differentiators

    • Natural Product Chemistry
    • Mass Spectrometry
    • Drug Discovery
    • Computational Chemistry
  • #3

    University of California, San Diego (UCSD)

    La Jolla, CA

    UCSD is recognized for its interdisciplinary research combining metabolomics, bioinformatics, and machine learning to advance natural product identification and drug discovery pipelines.

    Key Differentiators

    • Metabolomics
    • Mass Spectrometry
    • Bioinformatics
    • Machine Learning
  • #4

    Max Planck Institute for Chemical Ecology

    Jena, Thuringia

    This institute excels in studying chemical diversity in nature using mass spectrometry and computational tools, contributing to natural product discovery and ecological metabolomics.

    Key Differentiators

    • Chemical Ecology
    • Mass Spectrometry
    • Natural Product Chemistry
    • Computational Metabolomics
  • #5

    Novartis Institutes for BioMedical Research

    Cambridge, MA

    Novartis applies advanced mass spectrometry and AI-driven computational methods in pharmaceutical research, focusing on natural product drug discovery and prioritization.

    Key Differentiators

    • Drug Discovery
    • Mass Spectrometry
    • Machine Learning
    • Natural Products

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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Henry Thomas

Deputy Editor of The Analytical Scientist

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