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The Analytical Scientist / Issues / 2026 / March / Accelerating Sample Prep The Case for Automation
Sample Preparation Technology Innovation

Accelerating Sample Prep: The Case for Automation 

Manual sample preparation remains a major bottleneck that automation is now beginning to resolve

By Andrew Minett 03/19/2026 3 min read
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Clinical Scorecard: Accelerating Sample Prep: The Case for Automation

At a Glance

CategoryDetail
ConditionSample Preparation in Analytical Chemistry
Key MechanismsAutomation of extraction, mixing, filtration, and dilution to enhance workflow efficiency and accuracy.
Target PopulationLaboratories in environmental, pharmaceutical, and consumer safety testing.
Care SettingHigh-throughput testing facilities.

Key Highlights

  • Manual sample preparation is slow and prone to human error.
  • Automation can significantly reduce hands-on time and improve reproducibility.
  • Next generation automated systems support complex workflows and sustainability goals.
  • Standardizing preparation steps enhances accuracy at trace levels.
  • Comprehensive automation addresses rising sample loads and regulatory demands.

Guideline-Based Recommendations

Diagnosis

  • Identify bottlenecks in current manual sample preparation workflows.

Management

  • Implement comprehensive automation solutions for sample preparation.

Monitoring & Follow-up

  • Evaluate throughput and reproducibility post-automation implementation.

Risks

  • Ensure automated systems can handle complex matrices and workflows.

Patient & Prescribing Data

Not applicable; focuses on laboratory workflows.

Automation improves accuracy and efficiency in sample analysis.

Clinical Best Practices

  • Adopt multi-step automation for complex sample preparation.
  • Standardize critical preparation stages to reduce variability.
  • Utilize modern platforms that support various sample formats.

References

  • Source Article

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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References

  1. DAV Medina et al., “Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems,” Trends in Analytical Chemistry, 166, 117171 (2023).
  2. WA Khan et al., “Automation and high throughput sample analysis with various platforms in microextraction techniques: A need for ecofriendly, green, and cost-effective sample preparation approaches – A review,” Trends in Analytical Chemistry, 189, 118247 (2025).

About the Author(s)

Andrew Minett

Technical Director at ePrep

More Articles by Andrew Minett

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